NONLINEAR CONFORMATION OF SECONDARY PROTEIN FOLDING
نویسندگان
چکیده
منابع مشابه
Nonlinear conformation of secondary protein folding
A model to describe the mechanism of conformational dynamics in secondary protein based on matter interactions is proposed. The approach deploys the lagrangian method by imposing certain symmetry breaking. The protein backbone is initially assumed to be nonlinear and represented by the Sine-Gordon equation, while the nonlinear external bosonic sources is represented by φ interaction. It is argu...
متن کاملMonitoring Protein Conformation along the Pathway of Chaperonin-Assisted Folding
The GroEL/GroES chaperonin system mediates protein folding in the bacterial cytosol. Newly synthesized proteins reach GroEL via transfer from upstream chaperones such as DnaK/DnaJ (Hsp70). Here we employed single molecule and ensemble FRET to monitor the conformational transitions of a model substrate as it proceeds along this chaperone pathway. We find that DnaK/DnaJ stabilizes the protein in ...
متن کاملStudy on Properties of Protein Folding Conformation Network
Protein folding conformations take the form of networks, sets of conformations (vertices) joined together in pairs by links or edges. Protein folding conformation network is a complex network, and has scale-free property that many networks have in common. Understanding the scale-free property in the network of protein folding conformation, one can find the better conformation of protein folding...
متن کاملConformation changes and protein folding induced by \phi^4 interaction
A model to describe the mechanism of conformational dynamics in protein based on matter interactions using lagrangian approach and imposing certain symmetry breaking is proposed. Both conformation changes of proteins and the injected non-linear sources are represented by the bosonic lagrangian with an additional φ 4 interaction for the sources. In the model the spring tension of protein represe...
متن کاملProtein Stability, Folding, Disaggregation and Etiology of Conformational Malfunctions
Estimation of protein stability is important for many reasons: first providing an understanding of the basic thermodynamics of the process of folding, protein engineering, and protein stability plays important role in biotechnology especially in food and protein drug design. Today, proteins are used in many branches, including industrial processes, pharmaceutical industry, and medical fields. A...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: International Journal of Modern Physics: Conference Series
سال: 2012
ISSN: 2010-1945,2010-1945
DOI: 10.1142/s2010194512005181